Description

2-(4-Fluorobenzoyl)Pyridine is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated motifs into heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the fluorobenzoyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or fluorophores, for OLEDs and sensors.
• Chemical Biology Probes: Useful for designing molecular probes and tags that leverage the fluorine atom for studies like 19F NMR spectroscopy.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(4-Fluorobenzoyl)Pyridine
CAS No.	169955-75-3
Molecular Formula	C12H8FNO
Molecular Weight	201.20 g/mol
Synonyms	2-(4-Fluorobenzoyl)pyridine; 4-Fluoro-2-pyridinylphenylmethanone; (4-Fluorophenyl)(pyridin-2-yl)methanone; 2-Pyridyl 4-fluorophenyl ketone; 4'-Fluoro-2-pyridyl phenyl ketone; 2-(p-Fluorobenzoyl)pyridine; 169955-75-3; 4-Fluorobenzoylpyridine
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorobenzoyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR, NMR, and MS, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.