Description

4-Bromo-1-(4-Nitrobenzoyl)-3,4-Dihydro-1H-Benzo[B]Azepin-5(2H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzazepine-based drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize pharmacological properties of new chemical entities.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for high-throughput screening.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for advanced studies in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	4-Bromo-1-(4-Nitrobenzoyl)-3,4-Dihydro-1H-Benzo[B]Azepin-5(2H)-One
CAS No.	169879-06-5
Molecular Formula	C17H13BrN2O4
Molecular Weight	389.20 g/mol
Synonyms	4-Bromo-1-(4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-one; 4-Bromo-1-(4-nitrobenzoyl)-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one; 1H-Benzo[b]azepin-5(2H)-one, 4-bromo-3,4-dihydro-1-(4-nitrobenzoyl)-; 4-Bromo-1-(4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one; 169879-06-5; Benzoazepinone derivative, bromo-nitrobenzoyl substituted.
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-1-(4-Nitrobenzoyl)-3,4-Dihydro-1H-Benzo[B]Azepin-5(2H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch consistency supports your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.