Description

Ethyl 4-(4-Chlorophenyl)-3-Methyl-2,4-Dioxo-Butyrate is a high-purity, specialized organic intermediate featuring a β-keto ester moiety and a chlorophenyl group. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing active pharmaceutical ingredients (APIs) and other advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, or plant growth regulators, leveraging the chlorophenyl group's bioactivity.
• Fine Chemical Production: Used in the manufacture of complex dyes, pigments, and specialty polymers where specific aromatic and ketone functionalities are required.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis, including studies on Claisen condensations and cross-coupling reactions.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in regulatory testing.

Basic Information

Product Name	Ethyl 4-(4-Chlorophenyl)-3-Methyl-2,4-Dioxo-Butyrate
CAS No.	169544-41-6
Molecular Formula	C₁₃H₁₃ClO₄
Molecular Weight	268.69 g/mol
Synonyms	Ethyl 4-(4-chlorophenyl)-3-methyl-2,4-dioxobutanoate; 4-(4-Chlorophenyl)-3-methyl-2,4-dioxobutanoic acid ethyl ester; Butanoic acid, 4-(4-chlorophenyl)-3-methyl-2,4-dioxo-, ethyl ester; Ethyl 4-(p-chlorophenyl)-3-methyl-2,4-dioxobutyrate; 2,4-Dioxo-4-(4-chlorophenyl)-3-methylbutyric acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-(4-Chlorophenyl)-3-Methyl-2,4-Dioxo-Butyrate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and production use. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.