Description

2-Methylthiophenylboronic Acid is a versatile organoboron compound widely used as a key building block in modern synthetic chemistry. Its primary value lies in its role as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular assembly is required.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing substituted biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its ability to introduce specific aromatic groups into target molecules.
• Material Science Research: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, where tailored aryl-aryl linkages are necessary.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for biochemical and pharmacological research.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CROs/CMOs engaged in producing complex, bespoke organic molecules for clients.

Basic Information

Product Name	2-Methylthiophenylboronic Acid
CAS No.	168618-42-6
Molecular Formula	C7H9BOS
Molecular Weight	152.02 g/mol
Synonyms	(2-Methylthiophenyl)boronic Acid; 2-(Methylthio)benzeneboronic Acid; 2-Methylmercaptophenylboronic Acid; 2-Methylsulfanylbenzeneboronic Acid; 2-Methylthio-Benzeneboronic Acid; Boronic acid, B-(2-(methylthio)phenyl)-; 2-Methylthiophenyl-Boronic Acid
EINECS	Contact for details

Quality Control

Our 2-Methylthiophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.