Description

2-Methoxy-5-(5-Trifluoromethyl-Tetrazol-1-Yl)-Benzaldehyde is a high-value, multi-functional heterocyclic building block characterized by its benzaldehyde core, methoxy substituent, and a reactive 5-trifluoromethyltetrazole moiety. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where the trifluoromethyl and tetrazole groups are prized for modulating biological activity, lipophilicity, and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyltetrazole group.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, or organic electronic materials due to its aromatic aldehyde functionality.
• Chemical Biology & Proteomics: Can be utilized as a building block for click chemistry reagents or bioconjugation probes, exploiting the reactivity of the aldehyde and tetrazole groups.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions, condensations, and cyclizations to create complex heterocyclic systems.

Basic Information

Product Name	2-Methoxy-5-(5-Trifluoromethyl-Tetrazol-1-Yl)-Benzaldehyde
CAS No.	168267-11-6
Molecular Formula	C10H7F3N4O2
Molecular Weight	272.19 g/mol
Synonyms	5-(5-Trifluoromethyl-1H-tetrazol-1-yl)-2-methoxybenzaldehyde; 2-Methoxy-5-(5-trifluoromethyl-1H-tetrazol-1-yl)benzaldehyde; 1-(4-Formyl-2-methoxyphenyl)-5-(trifluoromethyl)-1H-tetrazole; Benzaldehyde, 2-methoxy-5-(5-(trifluoromethyl)-1H-tetrazol-1-yl)-; 168267-11-6
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-(5-Trifluoromethyl-Tetrazol-1-Yl)-Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality assurance supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive. Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.