Description

5-Hexenoicacid,2-Amino-3,3-Difluoro-(9Ci) CAS NO 168101-97-1 is a specialized fluorinated amino acid derivative, characterized by its unique difluoro and terminal alkene functional groups. This compound is a high-value building block prized for its role in introducing fluorine atoms and reactive handles into complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, peptide mimetics, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in protease inhibitors and targeted therapies.
• Agrochemical Research: Used in the synthesis of novel fluorinated pesticides and herbicides, leveraging fluorine's ability to enhance bioavailability and metabolic stability.
• Peptide Modification: Serves as a non-natural amino acid analog for creating fluorinated peptides with improved conformational stability and resistance to enzymatic degradation.
• Chemical Biology Probes: The alkene group allows for further functionalization via click chemistry, making it useful for creating labeled probes and bioconjugates.
• Material Science Precursor: Potential use in the synthesis of specialized fluorinated polymers and surface modifiers.

Basic Information

Product Name	5-Hexenoicacid,2-Amino-3,3-Difluoro-(9Ci)
CAS No.	168101-97-1
Molecular Formula	C6H9F2NO2
Molecular Weight	165.14 g/mol
Synonyms	2-Amino-3,3-difluoro-5-hexenoic acid; 3,3-Difluorovinylglycine; (2S)-2-Amino-3,3-difluorohex-5-enoic acid; 5-Hexenoic acid, 2-amino-3,3-difluoro-; 2-Amino-3,3-difluoropent-4-enoic acid; Difluorovinylglycine; 168101-97-1
EINECS	Contact for details

Quality Control

Our production of 2-Amino-3,3-difluoro-5-hexenoic acid adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and MS to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (by titration)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.