Description

3-Buten-2-One, 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, (3E)- is a high-value, advanced chemical intermediate featuring a conjugated enone system linked to a pinacol boronate ester, a versatile functional group for cross-coupling reactions. This compound is critical for enabling precise carbon-carbon bond formation, a fundamental step in constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly through Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials and functional polymers.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts.
• Fine Chemical Manufacturing: Integral for the custom synthesis of specialty chemicals and flavors & fragrances.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and chemical biology.

Basic Information

Product Name	3-Buten-2-One, 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, (3E)-
CAS No.	167896-52-8
Molecular Formula	C₁₀H₁₇BO₃
Molecular Weight	196.05 g/mol
Synonyms	(3E)-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-one; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-buten-2-one (E)-; (E)-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-one; trans-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-buten-2-one; 3-Buten-2-one, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, (E)-; Pinacol (E)-4-oxobut-2-en-1-ylboronate
EINECS	Contact for details

Quality Control

Every batch of 3-Buten-2-One, 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, (3E)- is produced and analyzed under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer and research standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (E/Z Ratio by HPLC)	≥ 95:5 (E:Z)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.