Description

trans-3-Hydroxy-1-Propenylboronic Acid Pinacol Ester is a high-value, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a versatile and stable building block, enabling precise carbon-carbon bond formation under mild conditions. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and other conjugated systems in drug discovery and material science.
• Pharmaceutical Intermediate: Used in the synthesis of complex target molecules for potential therapeutic agents.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Employed in the preparation of novel boron-containing ligands for catalytic systems.
• Material Science Research: A precursor for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the development of activity-based probes and other tools for studying biological processes.

Basic Information

Product Name	trans-3-Hydroxy-1-Propenylboronic Acid Pinacol Ester
CAS No.	167896-48-2
Molecular Formula	C11H21BO3
Molecular Weight	212.10 g/mol
Synonyms	(E)-3-Hydroxyprop-1-en-1-ylboronic acid pinacol ester; trans-3-Hydroxy-1-propenylboronic acid pinacol ester; (E)-3-Hydroxyallylboronic acid pinacol ester; 3-Hydroxy-trans-1-propenylboronic acid pinacol ester; Pinacol (E)-3-hydroxyprop-1-en-1-ylboronate; (E)-1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)prop-2-en-1-ol
EINECS	Contact for details

Quality Control

Our trans-3-Hydroxy-1-Propenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.