Description

4,4,5,5-Tetramethyl-2-(2-Methylallyl)-1,3,2-Dioxaborolane is a versatile and highly reactive organoboron compound, specifically a neopentyl glycol-derived allylboronate ester. Its core value proposition lies in its exceptional utility as a key building block in advanced organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura coupling. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise and efficient methods for constructing complex carbon-carbon bonds and introducing functional groups.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), enabling the construction of complex molecular architectures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through efficient coupling reactions.
• Polymer & Materials Science: Serves as a monomer or functionalization agent in the creation of advanced polymers, OLED materials, and liquid crystals.
• Organic Synthesis Reagent: A fundamental reagent for Suzuki-Miyaura cross-coupling reactions to form biaryl and other C-C bonds under mild conditions.
• Ligand & Catalyst Development: Employed in the preparation of novel boron-containing ligands and catalysts for asymmetric synthesis.
• Chemical Research: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2-Methylallyl)-1,3,2-Dioxaborolane
CAS No.	167773-10-6
Molecular Formula	C10H19BO2
Molecular Weight	182.07 g/mol
Synonyms	2-(2-Methylallyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Methylallyl)boronic acid neopentyl glycol ester; 2-Methylallylboronic acid pinacol ester; 2-MethylallylBPin; 2-MethylallylBpin; 2-Methylallyl Pinacol Boronate; 2-Methylprop-2-en-1-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(2-Methylallyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, GC, and HPLC, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for sensitive applications in pharmaceutical and advanced material synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.