Description

2-Buten-2-Ylboronic Acid Pinacol Ester is a high-purity organoboron reagent, specifically a protected boronic ester derivative. This compound is a critical building block in modern synthetic chemistry, enabling efficient carbon-carbon bond formation through cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of carbon-carbon bonds, essential for synthesizing complex organic molecules.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for introducing the 2-buten-2-yl moiety.
• Agrochemical Product Development: Employed in creating novel herbicides, fungicides, and insecticides that require specific olefinic side chains.
• Material Science Research: Serves as a monomer or building block for synthesizing organic electronic materials, polymers, and liquid crystals.
• Chemical Biology & Medicinal Chemistry: Utilized in the synthesis of molecular probes and tool compounds for biological target investigation.
• Process Chemistry & Scale-Up: The pinacol ester protection offers enhanced stability, making it suitable for multi-step synthesis and larger-scale manufacturing processes.

Basic Information

Product Name	2-Buten-2-Ylboronic Acid Pinacol Ester
CAS No.	167773-06-0
Molecular Formula	C10H19BO2
Molecular Weight	182.07 g/mol
Synonyms	2-Buten-2-ylboronic acid pinacol ester; (E)-2-Buten-2-ylboronic acid pinacol ester; trans-2-Buten-2-ylboronic acid pinacol ester; 2-Buten-2-yl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-2-Buten-2-yl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (E)-2-buten-2-ylboronate; (E)-1-Methyl-1-propenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Buten-2-Ylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed via NMR, HPLC, and GC to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain optimal stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.