Description

Ethanone, 2,2,2-Trifluoro-1-(3-Furanyl)- (9Ci) is a specialized fluorinated ketone building block, identified by CAS number 167405-27-8. This compound is valued for its unique trifluoromethyl ketone moiety attached to a furan heterocycle, offering distinct electronic and steric properties for advanced chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly as a key intermediate in the development of active ingredients and functional materials.

Application

This high-value fluorinated intermediate enables precise molecular design across several advanced fields:

• Pharmaceutical Intermediate: Serves as a critical building block for synthesizing novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Active Ingredient Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl group enhances bioactivity and environmental stability.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the development of specialty polymers, coatings, and liquid crystals with tailored properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial research for constructing complex heterocyclic frameworks and as a substrate in catalytic fluorination or cross-coupling reactions.
• Fluorine Chemistry Research: A valuable reagent for studying the influence of the trifluoromethyl ketone group on reaction mechanisms and physicochemical properties.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(3-Furanyl)- (9Ci)
CAS No.	167405-27-8
Molecular Formula	C7H3F3O2
Molecular Weight	176.09 g/mol
Synonyms	2,2,2-Trifluoro-1-(3-furanyl)ethanone; 3-Furyl Trifluoromethyl Ketone; 1-(3-Furanyl)-2,2,2-trifluoroethanone; 3-Acetylfuran, 2,2,2-trifluoro-; 3-Trifluoroacetylfuran; 3-Furyltrifluoromethylketone; 3-(Trifluoroacetyl)furan; 2,2,2-Trifluoro-1-(furan-3-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our production of Ethanone, 2,2,2-Trifluoro-1-(3-Furanyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. We employ advanced analytical techniques including GC, HPLC, NMR, and MS for comprehensive characterization and purity verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality management systems and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider using sealed containers under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Purity (GC/HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.