Description

1,2-Cyclopropanedicarboxylic acid, Monoethyl ester (9Ci) is a specialized cyclopropane derivative serving as a versatile chiral building block in advanced organic synthesis. Its constrained three-membered ring structure and functionalized ester group make it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor and other constrained scaffold designs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring can impart specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for the synthesis of polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Fine Chemical Production: Acts as a building block for the manufacture of complex fragrance and flavor compounds.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylic acid, Monoethyl ester (9Ci)
CAS No.	167113-73-7
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	Monoethyl cyclopropane-1,2-dicarboxylate; Ethyl hydrogen cyclopropane-1,2-dicarboxylate; 1,2-Cyclopropanedicarboxylic acid monoethyl ester; Cyclopropane-1,2-dicarboxylic acid monoethyl ester; 1-Carbethoxycyclopropane-2-carboxylic acid; 2-Carboxycyclopropanecarboxylic acid ethyl ester; Monoethyl 1,2-cyclopropanedicarboxylate; 9CI-labeled 1,2-cyclopropanedicarboxylic acid monoethyl ester
EINECS	Contact for details

Quality Control

Our production of 1,2-Cyclopropanedicarboxylic acid, Monoethyl ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.