Description

Methyl 3-(2,4-Difluorophenyl)Acrylate CAS NO 166883-00-7 is a high-purity fluorinated acrylate ester monomer, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the acrylate group combined with the electronic influence of the difluorophenyl moiety, enabling precise molecular design. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linker for creating specialty polymers with tailored properties such as chemical resistance, low surface energy, and specific optical characteristics.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic display and lighting technologies due to its influence on molecular polarity and alignment.
• Organic Synthesis Building Block: Utilized in Michael additions, cycloadditions, and polymerization reactions to introduce functionalized aromatic acrylate structures.

Basic Information

Product Name	Methyl 3-(2,4-Difluorophenyl)Acrylate
CAS No.	166883-00-7
Molecular Formula	C10H8F2O2
Molecular Weight	198.17 g/mol
Synonyms	Methyl (2E)-3-(2,4-Difluorophenyl)-2-propenoate; (E)-Methyl 3-(2,4-difluorophenyl)acrylate; 2-Propenoic acid, 3-(2,4-difluorophenyl)-, methyl ester, (2E)-; Methyl trans-3-(2,4-Difluorophenyl)acrylate; 3-(2,4-Difluorophenyl)acrylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(2,4-Difluorophenyl)Acrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (GC/HPLC)	≥ 99.0% (E-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.