Description

Ethanone, 2,2,2-Trifluoro-1-[3-(Methylthio)Phenyl]- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a methylthiophenyl substituent, making it a valuable fluorinated building block for advanced synthesis. This compound matters for its role in introducing the trifluoroacetyl group and sulfur-containing aromatic moiety into target molecules, enabling the development of compounds with modified electronic and steric properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in medicinal chemistry for probing enzyme active sites and developing protease inhibitors.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for protease inhibitors and other enzyme-targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for synthesizing fluorinated polymers or liquid crystals with unique optical and electronic properties.
• Chemical Biology Probe: Utilized as a building block for activity-based probes to study enzyme function and mechanism in biological systems.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and nucleophilic additions to construct complex, fluorinated aromatic ketones.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-[3-(Methylthio)Phenyl]- (9Ci)
CAS No.	166831-66-9
Molecular Formula	C9H7F3OS
Molecular Weight	220.21 g/mol
Synonyms	1-[3-(Methylthio)phenyl]-2,2,2-trifluoroethanone; 3'-(Methylthio)-2,2,2-trifluoroacetophenone; 2,2,2-Trifluoro-1-(3-methylsulfanylphenyl)ethanone; 3-Methylsulfanyl-α,α,α-trifluoroacetophenone; α,α,α-Trifluoro-3-(methylthio)acetophenone; 3-(Methylthio)phenyl trifluoromethyl ketone; TFMPK derivative
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-[3-(Methylthio)Phenyl]- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.