Description

2-[2-(Bromomethyl)Phenyl]-5,5-Dimethyl-1,3,2-Dioxaborinane is a versatile and high-value organoboron building block, specifically a bromomethyl-functionalized benzoxaborole derivative. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, allowing for the precise construction of complex biaryl and conjugated molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require reliable, high-purity intermediates for drug discovery, agrochemical development, and organic electronic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biphenyl or extended aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that leverage its boronate ester functionality for selective coupling.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and host molecules in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and as a scaffold for functional materials.
• Polymer Chemistry: Facilitates the synthesis of conjugated polymers and dendrimers with tailored electronic properties for advanced material applications.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological processes due to its reactive bromomethyl and boronate groups.

Basic Information

Product Name	2-[2-(Bromomethyl)Phenyl]-5,5-Dimethyl-1,3,2-Dioxaborinane
CAS No.	166821-88-1
Molecular Formula	C13H18BBrO2
Molecular Weight	297.00 g/mol
Synonyms	2-(2-Bromomethylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; (2-Bromobenzyl)boronic acid 5,5-dimethyl-1,3,2-dioxaborinane ester; 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 2-(2-Bromobenzyl)-5,5-dimethyl-1,3,2-dioxaborinane; Bromomethylphenyl dioxaborinane; 166821-88-1; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 2-[2-(Bromomethyl)Phenyl]-5,5-Dimethyl-1,3,2-Dioxaborinane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.