Description

5-Pyrimidinecarboxaldehyde, 1,2-Dihydro-2-Oxo- (9Ci) is a high-purity heterocyclic building block and key synthetic intermediate. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals due to its reactive aldehyde and pyrimidinone functionalities. It is primarily utilized by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create innovative molecular structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Bioconjugation: The aldehyde group can be utilized for site-specific labeling and conjugation of biomolecules.

Basic Information

Item	Details
Product Name	5-Pyrimidinecarboxaldehyde, 1,2-Dihydro-2-Oxo- (9Ci)
CAS No.	166757-62-6
Molecular Formula	C5H4N2O2
Molecular Weight	124.10 g/mol
Synonyms	2-Oxo-1,2-dihydropyrimidine-5-carbaldehyde; 5-Formyl-2-hydroxypyrimidine; 2-Hydroxypyrimidine-5-carboxaldehyde; 5-Pyrimidinecarboxaldehyde, 2-hydroxy-; 2(1H)-Pyrimidinone, 5-formyl-; 5-Carboxaldehyde-2-hydroxypyrimidine; 5-Formyluracil (tautomer)
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxaldehyde, 1,2-Dihydro-2-Oxo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.