Description

(Bromomethyl)Boronic Acid Pinacol Ester is a versatile organoboron building block, specifically a brominated boronic ester derivative. This compound is of significant value in modern synthetic chemistry as a key reagent for introducing functionalized methylene units via cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling: A crucial reagent for palladium-catalyzed coupling reactions to form new carbon-carbon bonds, enabling the synthesis of complex biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring functionalized benzyl or heterocyclic motifs.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides that contain boronic ester functional groups.
• Material Science & OLED Development: Serves as a building block for organic light-emitting diodes (OLEDs) and other electronic materials where precise molecular structure is critical.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Facilitates the creation of molecular probes and bioconjugates for diagnostic and research applications.

Basic Information

Product Name	(Bromomethyl)Boronic Acid Pinacol Ester
CAS No.	166330-03-6
Molecular Formula	C9H18BBrO2
Molecular Weight	249.96 g/mol
Synonyms	1-Bromo-1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methane; 2-(Bromomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Bromomethylboronic Acid Pinacol Ester; (Bromomethyl)boronic Acid Pinacol Ester; Pinacol (Bromomethyl)boronate; Bromomethyl Pinacol Boronate; (Bromomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our (Bromomethyl)Boronic Acid Pinacol Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B), HPLC, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive (hygroscopic) nature. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.