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Potassium (2-Fluorophenyl)Trifluoroborate CAS NO 166328-10-5
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CAS No.:166328-10-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Potassium (2-Fluorophenyl)Trifluoroborate is a versatile organoboron reagent, specifically a potassium aryltrifluoroborate salt. This compound is highly valued for its stability, ease of handling, and reactivity in key cross-coupling reactions, making it a critical building block in modern synthetic chemistry. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.
Application
- Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronate ester equivalent, enabling the synthesis of biaryl structures.
- Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic rings for enhanced metabolic stability and bioavailability.
- Agrochemical Compound Development: Employed in creating novel herbicides, fungicides, and insecticides where the 2-fluorophenyl moiety imparts specific biological activity.
- Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
- Material Science Research: Utilized in the development of organic electronic materials, such as OLEDs and semiconductors, where precise control over aromatic systems is required.
- Chemical Biology & Probe Synthesis: Acts as a building block for creating fluorescent tags, molecular probes, and other tools for biological research and diagnostics.
Basic Information
| Item | Detail |
|---|---|
| Product Name | Potassium (2-Fluorophenyl)Trifluoroborate |
| CAS No. | 166328-10-5 |
| Molecular Formula | C6H4BF4K |
| Molecular Weight | 193.99 g/mol |
| Synonyms | Potassium 2-Fluorophenyltrifluoroborate; Potassium (2-Fluorophenyl)trifluoroboranuide; (2-Fluorophenyl)trifluoroborate Potassium Salt; 2-Fluorophenyltrifluoroboronic Acid Potassium Salt; Potassium 2-Fluorobenzene-1-trifluoroborate; 2-Fluorophenyl-BF3K; Potassium (o-Fluorophenyl)trifluoroborate; Potassium Trifluoro(2-fluorophenyl)borate |
| EINECS | Contact for details |
Quality Control
Every batch of Potassium (2-Fluorophenyl)Trifluoroborate is manufactured under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including NMR (1H, 11B, 19F) and HPLC, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee product integrity and support your quality assurance processes.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or crystalline solid |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| 11B NMR Purity | ≥ 97% |
| Water Content (KF) | ≤ 2.0% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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