Description

Potassium 3,5-Bis(Trifluoromethyl)Phenyltrifluoroborate is a highly versatile organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its value lies in its exceptional stability and reactivity, making it a superior alternative to traditional boronic acids in cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce the highly lipophilic and electron-withdrawing 3,5-bis(trifluoromethyl)phenyl group into complex molecules.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other advanced catalytic processes.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and semiconductors, where fluorinated aromatic units improve charge transport and thermal stability.
• Chemical Library Production: Utilized in high-throughput and parallel synthesis for creating diverse compound libraries for drug discovery and screening.
• Fluorine Chemistry Studies: Acts as a stable and handleable source of a perfluorinated aryl moiety for investigating new fluorination methodologies and reaction mechanisms.

Basic Information

Product Name	Potassium 3,5-Bis(Trifluoromethyl)Phenyltrifluoroborate
CAS No.	166328-09-2
Molecular Formula	C8H3BF9K
Molecular Weight	320.01 g/mol
Synonyms	Potassium (3,5-Bis(trifluoromethyl)phenyl)trifluoroborate; 3,5-Bis(trifluoromethyl)phenyltrifluoroborate Potassium Salt; Potassium 3,5-Bis(trifluoromethyl)benzenetrifluoroborate; [3,5-Bis(trifluoromethyl)phenyl]trifluoroboronic Acid Potassium Salt; (3,5-Bis(trifluoromethyl)phenyl)potassium trifluoroboronate; B-(3,5-Bis(trifluoromethyl)phenyl)potassium trifluoroborane; Potassium Trifluoro[3,5-bis(trifluoromethyl)phenyl]borate
EINECS	Contact for details

Quality Control

Our Potassium 3,5-Bis(Trifluoromethyl)Phenyltrifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by 19F/11B NMR), purity (by HPLC), and moisture content (KF). Our quality system is designed to meet the stringent requirements of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) in a dry environment to prevent decomposition. For long-term storage, consider storing in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure (1H, 19F, 11B NMR)
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.