Description

4-Chloro-6-Fluoroindan-1-One is a high-purity fluorinated and chlorinated indanone derivative, serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) with specific biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds and scaling up production processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in research and development for creating new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in analytical laboratories.
• Organic Synthesis Scaffold: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis due to its versatile indanone core.

Basic Information

Product Name	4-Chloro-6-Fluoroindan-1-One
CAS No.	166250-01-7
Molecular Formula	C9H6ClFO
Molecular Weight	184.59 g/mol
Synonyms	4-Chloro-6-fluoro-2,3-dihydro-1H-inden-1-one; 4-Chloro-6-fluoroindan-1-one; 1H-Inden-1-one, 4-chloro-6-fluoro-2,3-dihydro-; 6-Fluoro-4-chloroindan-1-one; 4-Chloro-6-fluoro-1-indanone; 166250-01-7; 4-Cl-6-F-indan-1-one
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Fluoroindan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.