Description

2-Phenylethyl-1-Boronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. This compound matters for its stability and reactivity, serving as a key intermediate in the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing a phenethyl moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-alkyl linkages.
• Material Science: Employed in the creation of organic electronic materials, liquid crystals, and polymers through palladium-catalyzed coupling reactions.
• Chemical Research: Serves as a versatile reagent in academic and industrial laboratories for methodology development and library synthesis in medicinal chemistry.
• Cross-Coupling Reactions: Primarily utilized in Suzuki-Miyaura cross-coupling with various aryl or vinyl halides to form biaryl and styrene derivatives.

Basic Information

Product Name	2-Phenylethyl-1-Boronic Acid Pinacol Ester
CAS No.	165904-22-3
Molecular Formula	C14H21BO2
Molecular Weight	232.13 g/mol
Synonyms	2-Phenylethylboronic Acid Pinacol Ester; (2-Phenylethyl)boronic Acid Pinacol Ester; 2-Phenethylboronic Acid Pinacol Ester; 4,4,5,5-Tetramethyl-2-(2-phenylethyl)-1,3,2-dioxaborolane; B-(2-Phenylethyl)boronic Acid Pinacol Ester; Pinacol (2-Phenylethyl)boronate; 2-(2-Phenylethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Phenylethyl-1-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the needs of research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.