Description

(1S,2S,3R,5S)-(+)-2,3-Pinanediol 4-Bromobutylboronate Ester is a high-purity, chiral boronic ester derivative, a crucial intermediate in modern asymmetric synthesis. Its primary value lies in its role as a versatile building block for constructing complex molecules with precise stereochemical control. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Asymmetric Synthesis: A key chiral auxiliary or ligand precursor in catalytic asymmetric reactions, including Suzuki-Miyaura cross-couplings.
• Pharmaceutical Intermediates: Critical for the synthesis of complex, stereochemically defined drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel, chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Material Science: Serves as a building block for creating functionalized polymers and advanced organic materials with specific properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and enzyme functions.
• Process Chemistry: Utilized in the scale-up and optimization of synthetic routes for commercial production of fine chemicals.

Basic Information

Product Name	(1S,2S,3R,5S)-(+)-2,3-Pinanediol 4-Bromobutylboronate Ester
CAS No.	165881-36-7
Molecular Formula	C₁₄H₂₄BBrO₂
Molecular Weight	315.06 g/mol
Synonyms	(+)-Pinanediol 4-Bromobutylboronate; (1S,2S,3R,5S)-Pinanediol 4-Bromobutylboronate; 4-Bromobutylboronic Acid Pinanediol Ester; 4-Bromobutylboronic Acid (1S,2S,3R,5S)-(-)-2,10-Camphanediol Ester; B-(4-Bromobutyl)-4,4,5,5-tetramethyl-2-(1S,2S,3R,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl)-1,3,2-dioxaborolane (long-form IUPAC); 4-BBBE; BromobutylBPin
EINECS	Contact for details

Quality Control

Our (1S,2S,3R,5S)-(+)-2,3-Pinanediol 4-Bromobutylboronate Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and NMR spectroscopy, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.