Description

(2S,4R)-2-Methyl-Tetrahydro-2H-Pyran-4-Ol CAS NO 165876-16-4 is a high-purity, chiral building block and intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a critical component for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and production in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Asymmetric Catalysis Ligand Precursor: Used to develop and synthesize chiral ligands and organocatalysts for enantioselective reactions.
• Agrochemical Synthesis: Serves as a building block for creating chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Flavor and Fragrance Industry: Employed in the synthesis of complex, naturally-derived odorants and flavoring agents with specific stereochemical notes.
• Material Science Research: Acts as a monomer or functional modifier in the development of specialized polymers with tailored properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and stereochemistry.

Basic Information

Product Name	(2S,4R)-2-Methyl-Tetrahydro-2H-Pyran-4-Ol
CAS No.	165876-16-4
Molecular Formula	C6H12O2
Molecular Weight	116.16 g/mol
Synonyms	(2S,4R)-2-Methyl-4-hydroxytetrahydropyran; (2S,4R)-2-Methyltetrahydro-2H-pyran-4-ol; 4-Hydroxy-2-methyltetrahydropyran (stereospecific); cis-2-Methyltetrahydropyran-4-ol; (2S,4R)-2-Methyl-4-THP-ol; 2-Methyl-4-hydroxyoxane; Chiral THP alcohol derivative
EINECS	Contact for details

Quality Control

Our (2S,4R)-2-Methyl-Tetrahydro-2H-Pyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.