Description

Carbamic Acid, [(1S)-1-(2R)-Oxiranylethyl]-, 1,1-Dimethylethyl Ester (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant value in advanced organic synthesis. This compound matters for its role as a critical building block in the production of complex, biologically active molecules, offering precise control over stereochemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel therapeutics, particularly those targeting central nervous system and cardiovascular diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for protease inhibitors and other enzyme-targeted drugs.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Peptidomimetic Development: Used in the design and synthesis of peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for agrochemical and material science applications.

Basic Information

Product Name	Carbamic Acid, [(1S)-1-(2R)-Oxiranylethyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	165683-90-9
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	(2R,3S)-1-[(tert-Butoxycarbonyl)amino]-3,4-epoxy-2-butanol; tert-Butyl N-[(2S,3R)-3,4-epoxy-1-hydroxybutan-2-yl]carbamate; (2S,3R)-1-tert-Butoxycarbonylamino-3,4-epoxy-2-butanol; BOC-Aminoepoxybutanol; (2R,3S)-Epoxybutanol BOC-carbamate; tert-Butyl ((2S,3R)-3,4-epoxy-1-hydroxybutan-2-yl)carbamate; 1,1-Dimethylethyl N-[(1S)-1-[(2R)-oxiranylethyl]]carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1S)-1-(2R)-Oxiranylethyl]-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.