Description

[1(S)-Methyl-2(S),3-Epoxypropyl]-Carbamic Acid tert-Butyl Ester is a high-value, stereochemically defined chiral building block and key pharmaceutical intermediate. Its core value lies in its unique epoxide and protected amine functionality, enabling the stereoselective synthesis of complex molecules. This compound is essential for research and production in the pharmaceutical industry, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other complex therapeutic molecules.
• Asymmetric Synthesis: Used in the construction of chiral centers in natural products and bioactive compounds via ring-opening reactions of the epoxide moiety.
• Peptidomimetics & Amino Acid Derivatives: Serves as a protected precursor for non-natural amino acids and peptide analogs.
• Agrochemical Research: Employed in the development of chiral active ingredients for crop protection with enhanced efficacy.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic and medicinal chemistry.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals requiring high stereochemical purity.

Basic Information

Product Name	[1(S)-Methyl-2(S),3-Epoxypropyl]-Carbamic Acid tert-Butyl Ester
CAS No.	165683-88-5
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	(2S,3S)-1-tert-Butoxycarbonylamino-3-methyl-1,2-epoxybutane; (2S,3S)-1-[(tert-Butoxycarbonyl)amino]-3-methyl-1,2-epoxybutane; tert-Butyl N-[(2S,3S)-2,3-epoxy-3-methylbutyl]carbamate; (2S,3S)-Boc-Amino-3-methyl-1,2-epoxybutane; (2S,3S)-1-(Boc-amino)-3-methyl-1,2-epoxybutane; (2S,3S)-N-Boc-3-methyl-1,2-epoxybutylamine; (2S,3S)-3-Methyl-1,2-epoxybutylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our [1(S)-Methyl-2(S),3-Epoxypropyl]-Carbamic Acid tert-Butyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high stereochemical purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and diastereomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Diastereomeric Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.