Description

5-Hexen-2-One, 3,3-Difluoro-1-Hydroxy- is a specialized fluorinated hydroxy ketone building block with a terminal alkene group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D chemists for constructing novel active ingredients. The compound's reactivity profile allows for selective modifications at both the hydroxyl and alkene sites, enabling the creation of diverse chemical libraries.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting novel fluorinated compounds.
• Agrochemical Synthesis: Used in the R&D of advanced pesticides and herbicides, where the introduction of fluorine atoms can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and fluorinated materials with unique surface properties.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex organic molecules, leveraging its difluoro and hydroxy functionalities for further chemical transformations.
• Ligand and Catalyst Development: Utilized as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	5-Hexen-2-One, 3,3-Difluoro-1-Hydroxy-
CAS No.	165465-52-1
Molecular Formula	C6H8F2O2
Molecular Weight	150.12 g/mol
Synonyms	3,3-Difluoro-1-hydroxy-5-hexen-2-one; 1-Hydroxy-3,3-difluoro-5-hexen-2-one; 5-Hexen-2-one, 3,3-difluoro-1-hydroxy-; 3,3-Difluoro-1-hydroxyhex-5-en-2-one; (CAS 165465-52-1)
EINECS	Contact for details

Quality Control

Every batch of 5-Hexen-2-One, 3,3-Difluoro-1-Hydroxy- is produced and tested under strict quality management protocols to ensure consistency and purity for research applications. Our standard quality commitment includes comprehensive analytical characterization using techniques such as NMR, HPLC, and GC to verify identity and assay. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results. We support custom synthesis and can tailor specifications to meet the precise requirements of your project.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.