Description

16-Hydroxy-2-oxocleroda-3,13-dien-15,16-olide is a clerodane-type diterpenoid lactone, a compound of significant interest in advanced organic synthesis and pharmaceutical research. Its unique polycyclic structure with multiple functional groups makes it a valuable intermediate for developing novel bioactive molecules. This high-purity compound is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, natural product synthesis, and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates targeting inflammation, pain, and microbial infections.
• Medicinal Chemistry Research: Used as a reference standard or a core scaffold for structure-activity relationship (SAR) studies to explore new biological activities.
• Natural Product Synthesis: Acts as a sophisticated intermediate in the total or semi-synthesis of complex clerodane diterpenoids and their analogs.
• Biochemical Research: Employed in studies investigating enzyme inhibition and other specific biological interactions due to its defined stereochemistry.
• High-Value Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals for agrochemical or material science applications.

Basic Information

Item	Detail
Product Name	16-Hydroxy-2-oxocleroda-3,13-dien-15,16-olide
CAS No.	165459-53-0
Molecular Formula	C20H26O5
Molecular Weight	346.42 g/mol
Synonyms	16-Hydroxy-2-oxocleroda-3,13E-dien-15,16-olide; 2-Oxo-16-hydroxycleroda-3,13-dien-15,16-olide; Clerodane diterpene lactone; (13E)-16-Hydroxy-2-oxocleroda-3,13-dien-15,16-olide; 15,16-Seco-16-hydroxycleroda-3,13-dien-2,15-dioic acid 16,15-lactone
EINECS	Contact for details

Quality Control

Our 16-Hydroxy-2-oxocleroda-3,13-dien-15,16-olide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.