Description

4,4-Difluoro-1-p-Tolyl-Butane-1,3-Dione is a specialized fluorinated diketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular structure, which serves as a versatile precursor for synthesizing complex heterocyclic compounds and fluorinated pharmaceuticals. This high-purity intermediate is primarily needed by research and development laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Ligand Synthesis: Used in the preparation of β-diketone ligands for metal-organic frameworks (MOFs) and coordination chemistry.
• Heterocyclic Chemistry: Serves as a crucial precursor for constructing fluorinated pyrazoles, isoxazoles, and other nitrogen-containing heterocycles.
• Material Science Research: Employed in the development of novel fluorinated polymers and organic electronic materials.
• Agrochemical Synthesis: Acts as an intermediate in the research and development of new fluorinated pesticides and herbicides.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in related chemical processes.

Basic Information

Item	Details
Product Name	4,4-Difluoro-1-p-Tolyl-Butane-1,3-Dione
CAS No.	165328-11-0
Molecular Formula	C11H10F2O2
Molecular Weight	212.19 g/mol
Synonyms	1-(4-Methylphenyl)-4,4-difluorobutane-1,3-dione; 4,4-Difluoro-1-(4-methylphenyl)-1,3-butanedione; p-Tolyl-4,4-difluorodiketone; 4,4-Difluoro-1-(p-tolyl)butane-1,3-dione; 4,4-Difluoro-1-(4-methylphenyl)-1,3-butanedione; DFPTBD
EINECS	Contact for details

Quality Control

Our 4,4-Difluoro-1-p-Tolyl-Butane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is sensitive to strong alkali and should be kept separate from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.