Description

2-Bromo-4'-Chloroacetophenone is a versatile and high-purity organic intermediate of significant importance in advanced chemical synthesis. Its unique halogenated structure makes it a critical building block for constructing complex molecules in regulated industries. This compound is essential for research and production within the pharmaceutical, agrochemical, and specialty chemical sectors, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with halogen-substituted aromatic rings.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and pesticides, leveraging its reactive bromo and chloro functional groups.
• Chemical Research & Development: Serves as a valuable reagent in organic chemistry labs for studying substitution reactions and synthesizing novel compounds.
• Liquid Crystal & OLED Material Precursor: Employed in the production of advanced electronic materials and display technologies.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex colorants and functional dyes.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions, such as Suzuki or Heck couplings, to form carbon-carbon bonds.

Basic Information

Product Name	2-Bromo-4'-Chloroacetophenone
CAS No.	165120-40-1
Molecular Formula	C8H6BrClO
Molecular Weight	233.49 g/mol
Synonyms	1-(4-Chlorophenyl)-2-bromoethanone; 2-Bromo-1-(4-chlorophenyl)ethanone; 4'-Chloro-2-bromoacetophenone; p-Chlorophenacyl bromide; α-Bromo-4'-chloroacetophenone; 4-Chlorophenacyl bromide; 2-Bromo-4'-chloroacetophenone; Ethanone, 2-bromo-1-(4-chlorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4'-Chloroacetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	88°C - 92°C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.