Description

4-Chloromethylphenylboronic Acid is a versatile bifunctional organoboron building block, essential for modern synthetic chemistry. Its unique structure, featuring both a reactive boronic acid group and a chloromethyl handle, makes it a critical intermediate for constructing complex molecules via cross-coupling and subsequent functionalization. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel biaryl compounds with potential therapeutic activity.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its ability to introduce aromatic chloromethyl motifs.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis.
• Polymer and Material Science: Acts as a monomer or functionalization agent in the production of specialty polymers, including boron-containing resins and OLED materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis and R&D: An invaluable tool for medicinal chemistry and process research in constructing diverse chemical libraries.

Basic Information

Product Name	4-Chloromethylphenylboronic Acid
CAS No.	164413-77-8
Molecular Formula	C7H8BClO2
Molecular Weight	170.40 g/mol
Synonyms	(4-(Chloromethyl)phenyl)boronic acid; p-(Chloromethyl)phenylboronic acid; 4-(Chloromethyl)benzeneboronic acid; B-(4-(Chloromethyl)phenyl)boronic acid; 1-Chloromethyl-4-boronic acid benzene; (4-Chloromethyl)benzeneboronic acid; 4-Chloromethylbenzeneboronic Acid; (p-Chloromethylphenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 4-Chloromethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.