Description

3-(Ethoxymethylene)-1,1,1-Trifluoro-2,4-pentanedione is a versatile fluorinated β-diketone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a reactive ethoxymethylene group and trifluoromethyl functionality, makes it an invaluable precursor for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, where it is used to introduce fluorinated motifs that can dramatically alter a compound's bioavailability, stability, and activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated heterocycles or complex chelating agents.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides where the fluorine atom enhances lipophilicity and biological activity.
• Ligand for Metal Complexes: Acts as a chelating agent for transition metals, forming stable complexes used in catalysis and materials science.
• Advanced Material Precursor: Building block for fluorinated polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel fluorinated compounds.

Basic Information

Item	Details
Product Name	3-(Ethoxymethylene)-1,1,1-Trifluoro-2,4-pentanedione
CAS No.	164342-38-5
Molecular Formula	C8H9F3O3
Molecular Weight	210.15 g/mol
Synonyms	3-(Ethoxymethylene)-1,1,1-trifluoropentane-2,4-dione; 1,1,1-Trifluoro-3-(ethoxymethylene)-2,4-pentanedione; Ethoxymethylenetrifluoroacetylacetone; TFAA enol ether; 4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (tautomeric form); F3C-CO-CH=C(OCH2CH3)-CO-CH3; 3-Ethoxymethylene-1,1,1-trifluoroacetylacetone
EINECS	Contact for details

Quality Control

Our production of 3-(Ethoxymethylene)-1,1,1-Trifluoro-2,4-pentanedione adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality systems are designed to meet the rigorous demands of GMP and ISO standards for chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.