Description

4-Penten-2-One, 1,1,1-Trifluoro-3,4-Dimethyl- is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a reactive α,β-unsaturated ketone moiety adjacent to a trifluoromethyl group, makes it a valuable precursor for introducing fluorinated motifs into complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It enables the synthesis of novel compounds with potentially enhanced biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated scaffolds to modulate bioavailability and potency.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group can enhance efficacy and environmental profile.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and coatings with unique surface properties and chemical resistance.
• Organic Synthesis Building Block: Employed in Michael additions, cycloadditions, and other carbon-carbon bond forming reactions to construct complex, fluorinated organic architectures.
• Ligand and Catalyst Development: Useful for preparing novel fluorinated ligands for catalysis or as a substrate in asymmetric synthesis studies.

Basic Information

Item	Details
Product Name	4-Penten-2-One, 1,1,1-Trifluoro-3,4-Dimethyl-
CAS No.	163882-70-0
Molecular Formula	C7H9F3O
Molecular Weight	166.14 g/mol
Synonyms	1,1,1-Trifluoro-3,4-dimethyl-4-penten-2-one; 3,4-Dimethyl-1,1,1-trifluoro-4-penten-2-one; 4-Penten-2-one, 1,1,1-trifluoro-3,4-dimethyl-; 3,4-Dimethyl-1,1,1-trifluoropent-4-en-2-one; TFDPO (abbrev.); 1,1,1-Trifluoro-3,4-dimethylpent-4-en-2-one
EINECS	Contact for details

Quality Control

Every batch of 4-Penten-2-One, 1,1,1-Trifluoro-3,4-Dimethyl- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and process chemistry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to ensure batch-to-batch consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive nature of α,β-unsaturated ketones, prolonged storage should be under an inert atmosphere such as nitrogen or argon to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.