Description

3-Penten-2-One, 1,1,1-Trifluoro-3,4-Dimethyl- is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the trifluoromethyl group, enabling the efficient introduction of fluorine atoms to modulate the physical and biological properties of target molecules. This compound is essential for R&D chemists and process development scientists working in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate for creating novel active ingredients with enhanced metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in the development of new drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved biological activity, environmental stability, and selective action.
• Material Science Research: Serves as a monomer or precursor for developing novel fluorinated polymers and specialty materials with unique surface properties, chemical resistance, and optical characteristics.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) due to its ability to influence dielectric constant and molecular alignment.
• Advanced Organic Synthesis: A versatile reagent for constructing complex molecular architectures via reactions like Michael additions, aldol condensations, and nucleophilic substitutions, leveraging its activated carbonyl and fluorinated moiety.

Basic Information

Product Name	3-Penten-2-One, 1,1,1-Trifluoro-3,4-Dimethyl-
CAS No.	163882-69-7
Molecular Formula	C7H9F3O
Molecular Weight	166.14 g/mol
Synonyms	1,1,1-Trifluoro-3,4-dimethyl-3-penten-2-one; 3,4-Dimethyl-1,1,1-trifluoro-3-penten-2-one; 3,4-Dimethyl-1,1,1-trifluoropent-3-en-2-one; 1,1,1-Trifluoro-3,4-dimethylpent-3-en-2-one; Trifluoroacetyl isopropenyl acetyl; TFIPA (abbreviation); Fluorinated pentenone derivative
EINECS	Contact for details

Quality Control

Every batch of 3-Penten-2-One, 1,1,1-Trifluoro-3,4-Dimethyl- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is available for each lot, confirming identity, purity, and impurity profiles as determined by GC, HPLC, and NMR. Our quality commitment supports compliance with ISO and cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Keep away from heat, sparks, and open flames. Store separately from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.