Description

Oxiranecarboxaldehyde, 3-(Trimethylsilyl)-, trans- (9Ci) is a high-value, organosilicon-functionalized epoxide building block. This compound is prized for its dual reactivity, offering both an aldehyde and a strained oxirane ring for sequential or orthogonal functionalization in advanced synthetic schemes. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring silicon-containing bioactive motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where the silyl group modulates properties like lipophilicity and stability.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty silicones, epoxy resins, and functional polymers with tailored surface properties.
• Ligand & Catalyst Development: Employed in the preparation of sophisticated ligands for asymmetric catalysis and organometallic complexes.
• Chemical Biology Probes: Useful for bioconjugation and labeling strategies due to its selective reactivity with amines and thiols.
• Fine Chemical Synthesis: A versatile starting material for multi-step synthesis of complex natural products and specialty chemicals.

Basic Information

Product Name	Oxiranecarboxaldehyde, 3-(Trimethylsilyl)-, trans- (9Ci)
CAS No.	163748-82-1
Molecular Formula	C8H16O2Si
Molecular Weight	172.30 g/mol
Synonyms	trans-3-(Trimethylsilyl)oxiranecarboxaldehyde; (2R,3S)-3-(Trimethylsilyl)oxiranecarbaldehyde; 3-(Trimethylsilyl)glycidaldehyde; Glycidylaldehyde, 3-(trimethylsilyl)-, trans-; 2-[(1S,2S)-2-Formyl-2-(trimethylsilyl)ethyl]oxirane; (2R,3S)-2,3-Epoxy-3-(trimethylsilyl)propanal; 3-Trimethylsilylglycidaldehyde; (trans)-3-(Trimethylsilyl)glycidic aldehyde
EINECS	Contact for details

Quality Control

Our Oxiranecarboxaldehyde, 3-(Trimethylsilyl)-, trans- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere. Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed and handled under dry conditions to prevent hydrolysis and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (trans isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.