Description

Ethyl 3-Isopropyl-1,2,4-Oxadiazole-5-Carboxylate is a high-value heterocyclic building block and synthetic intermediate. This compound is prized for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the versatile 1,2,4-oxadiazole moiety into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the oxadiazole ring contributes to biological activity.
• Material Science Research: Serves as a building block for creating functional organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes and activity-based protein profiling (ABPP) agents.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis & Scale-Up: Supplied for custom manufacturing projects, from gram-scale feasibility studies to multi-kilogram pilot plant production.

Basic Information

Product Name	Ethyl 3-Isopropyl-1,2,4-Oxadiazole-5-Carboxylate
CAS No.	163719-70-8
Molecular Formula	C8H12N2O3
Molecular Weight	184.19 g/mol
Synonyms	5-Carbethoxy-3-isopropyl-1,2,4-oxadiazole; Ethyl 3-(1-methylethyl)-1,2,4-oxadiazole-5-carboxylate; 3-Isopropyl-1,2,4-oxadiazole-5-carboxylic acid ethyl ester; 1,2,4-Oxadiazole-5-carboxylic acid, 3-(1-methylethyl)-, ethyl ester; Ethyl 3-isopropyl-[1,2,4]oxadiazole-5-carboxylate; 3-Isopropyl-5-ethoxycarbonyl-1,2,4-oxadiazole
EINECS	Contact for details

Quality Control

Our Ethyl 3-Isopropyl-1,2,4-Oxadiazole-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.