Description

D-Threo-Pentitol, 1,2-Anhydro-4,5-Dideoxy-2-C-Ethynyl- (9Ci) is a specialized, high-purity chemical building block featuring a unique anhydro and ethynyl-modified pentitol structure. This compound is valued for its role as a key chiral intermediate in advanced organic synthesis, enabling the construction of complex molecules with precise stereochemistry. It is primarily utilized by research institutions and pharmaceutical development teams working on nucleoside analogs, carbohydrate-based therapeutics, and novel molecular probes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Carbohydrate Chemistry Research: Serves as a versatile building block for synthesizing modified sugars, glycomimetics, and complex oligosaccharides for biological studies.
• Chemical Biology Probe Development: The ethynyl group allows for bioorthogonal conjugation (e.g., via click chemistry) to create labeled probes for studying biological processes.
• Organic Synthesis: Used in stereoselective synthesis to introduce specific chiral centers into larger, more complex organic molecules.
• Academic & Industrial R&D: Essential for exploratory chemistry in both university laboratories and corporate R&D departments focused on medicinal chemistry and new material science.

Basic Information

Product Name	D-Threo-Pentitol, 1,2-Anhydro-4,5-Dideoxy-2-C-Ethynyl- (9Ci)
CAS No.	163259-76-5
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	1,2-Anhydro-4,5-dideoxy-2-C-ethynyl-D-threo-pentitol; 2-C-Ethynyl-1,2-anhydro-4,5-dideoxy-D-threo-pentitol; 2-C-Ethynyl-1,2-anhydro-4,5-dideoxypentitol, D-threo-; D-threo-1,2-Anhydro-4,5-dideoxy-2-C-ethynylpentitol; 2-C-Ethynyl-1,2-anhydro-4,5-dideoxy-D-threo-pentitol (9CI); 163259-76-5; Anhydro-dideoxy-ethynylpentitol derivative
EINECS	Contact for details

Quality Control

Our D-Threo-Pentitol, 1,2-Anhydro-4,5-Dideoxy-2-C-Ethynyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.