Description

Methyl 4-Oxo-5,6,7,8-Tetrahydro-4H-Pyrazolo[1,5-A][1,4]Diazepine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate (API) characterized by its fused pyrazolo-diazepine heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) and oncology drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Drug Discovery & Development: Used in the R&D pipeline for creating potential candidates with anxiolytic, sedative, or anti-cancer properties.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up synthesis under cGMP conditions.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and novel synthetic pathways.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and pharmacological assays.

Basic Information

Product Name	Methyl 4-Oxo-5,6,7,8-Tetrahydro-4H-Pyrazolo[1,5-A][1,4]Diazepine-2-Carboxylate
CAS No.	163213-38-5
Molecular Formula	C10H11N3O3
Molecular Weight	221.21 g/mol
Synonyms	Methyl 4-oxo-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine-2-carboxylate; 4H-Pyrazolo[1,5-a][1,4]diazepine-2-carboxylic acid, 5,6,7,8-tetrahydro-4-oxo-, methyl ester; Methyl 4-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[1,5-a][1,4]diazepine-2-carboxylate; Pyrazolo[1,5-a][1,4]diazepine-2-carboxylic acid methyl ester derivative; CAS 163213-38-5
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Oxo-5,6,7,8-Tetrahydro-4H-Pyrazolo[1,5-A][1,4]Diazepine-2-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.