Description

4-Tetrahydropyranoxy-2-Methoxybenzaldehyde is a specialized aromatic aldehyde derivative, serving as a crucial protected intermediate in advanced organic synthesis. Its value lies in providing a versatile and reactive aldehyde functionality while the tetrahydropyranyl (THP) group offers orthogonal protection for phenolic hydroxyls, enabling complex, multi-step synthetic sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex organic molecules where selective deprotection strategies are required.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the production of specialty chemicals, fragrances, and advanced materials requiring protected aldehyde chemistry.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides.
• Academic & R&D Laboratories: Employed in methodological studies and the synthesis of novel organic compounds for research purposes.
• Ligand and Catalyst Development: Useful for constructing complex ligand frameworks in coordination chemistry and catalysis.

Basic Information

Product Name	4-Tetrahydropyranoxy-2-Methoxybenzaldehyde
CAS No.	163041-68-7
Molecular Formula	C14H18O4
Molecular Weight	250.29 g/mol
Synonyms	2-Methoxy-4-(tetrahydro-2H-pyran-2-yloxy)benzaldehyde; 4-(Tetrahydro-2H-pyran-2-yloxy)-2-methoxybenzaldehyde; Benzaldehyde, 2-methoxy-4-(tetrahydro-2H-pyran-2-yloxy)-; 4-(Oxan-2-yloxy)-2-methoxybenzaldehyde; THP-protected Vanillin Aldehyde Derivative; 2-Methoxy-4-(oxan-2-yloxy)benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Tetrahydropyranoxy-2-Methoxybenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.