Description

1,2,4-Oxadiazole-3-Carboximidamide,n-Hydroxy-5-Methyl- is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its unique oxadiazole core functionalized with amidoxime and methyl groups makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments focused on pharmaceutical discovery, agrochemical development, and materials science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Research: Serves as a core structure for synthesizing new candidates for herbicides, fungicides, and insecticides, leveraging the bioactivity of the oxadiazole ring.
• Ligand Synthesis in Coordination Chemistry: Used to prepare chelating ligands for metal complexes, applicable in catalysis and material science.
• Polymer & Material Science: Incorporated as a functional monomer or cross-linking agent to impart specific thermal or chemical properties to advanced polymers.
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	1,2,4-Oxadiazole-3-Carboximidamide,n-Hydroxy-5-Methyl-
CAS No.	162969-65-5
Molecular Formula	C4H6N4O2
Molecular Weight	142.12 g/mol
Synonyms	5-Methyl-1,2,4-oxadiazole-3-carboximidamide, N-hydroxy-; 3-(N-Hydroxycarbamimidoyl)-5-methyl-1,2,4-oxadiazole; N-Hydroxy-5-methyl-1,2,4-oxadiazole-3-carboximidamide; 5-Methyl-3-(N-hydroxycarbamimidoyl)-1,2,4-oxadiazole; 1,2,4-Oxadiazole-3-carboximidamide, N-hydroxy-5-methyl-; Amidoxime derivative of 5-methyl-1,2,4-oxadiazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1,2,4-Oxadiazole-3-Carboximidamide,n-Hydroxy-5-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.