Description

Polygalasaponin V is a high-purity, bioactive saponin compound derived from the *Polygala* genus of plants. This specialized phytochemical is valued for its significant role in advanced research and development within the life sciences sector. It serves as a critical reference standard and active ingredient for pharmaceutical, nutraceutical, and cosmetic applications, where precise biological activity is paramount.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of herbal medicines and botanical extracts in quality control laboratories.
• Neuropharmacology Research: Investigated for its potential neuroprotective, anti-depressant, and cognitive-enhancing properties in preclinical studies.
• Natural Product Drug Discovery: Serves as a lead compound or biochemical tool for developing new therapeutic agents targeting inflammation and CNS disorders.
• Nutraceutical Formulation: Incorporated into high-end dietary supplements aimed at supporting cognitive function and stress response.
• Cosmeceutical Ingredient: Utilized in advanced skincare formulations for its purported anti-inflammatory and soothing benefits.
• Academic & Institutional Research: Employed in universities and research institutes for pharmacological, metabolic, and biosynthetic pathway studies.

Basic Information

Product Name	Polygalasaponin V
CAS No.	162857-65-0
Molecular Formula	C₅₉H₉₆O₂₇
Molecular Weight	1221.4 g/mol
Synonyms	Tenufoliside A; Polygalasaponin V; 3-O-β-D-Glucopyranosyl (1→3)-β-D-glucopyranosyl presenegenin 28-O-β-D-apiofuranosyl(1→3)-β-D-xylopyranosyl(1→4)-α-L-rhamnopyranosyl(1→2)-[β-D-apiofuranosyl(1→3)]-β-D-fucopyranosyl ester; Presenegenin 3-O-β-D-glucosyl-(1→3)-β-D-glucoside 28-O-β-D-apiosyl-(1→3)-β-D-xylosyl-(1→4)-α-L-rhamnosyl-(1→2)-[β-D-apiosyl-(1→3)]-β-D-fucoside
EINECS	Contact for details

Quality Control

Our Polygalasaponin V is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for identification, and residual solvent analysis to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95.0%
Loss on Drying	≤5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm
Assay (HPLC)	90.0% - 110.0% of labeled amount

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.