Description

Polygalasaponin Ii is a specific, high-purity saponin compound isolated from the Polygala genus of plants. This compound is valued for its role as a key reference standard and active pharmaceutical ingredient (API) in research and development. It is primarily utilized by the pharmaceutical, nutraceutical, and academic research sectors for its bioactive properties. The product is supplied with comprehensive analytical documentation to ensure traceability and reliability for critical applications.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of Polygala-based drugs and herbal extracts in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical starting material or intermediate in the synthesis and formulation of neuroprotective or anti-inflammatory drug candidates.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate mechanisms of action related to saponin bioactivity.
• Nutraceutical and Cosmetic Development: Incorporated into high-end formulations for its potential antioxidant and skin-beneficial properties.
• Analytical Method Development: Essential for developing and validating chromatographic methods (e.g., HPLC, LC-MS) for saponin profiling.

Basic Information

Product Name	Polygalasaponin Ii
CAS No.	162857-62-7
Molecular Formula	C59H96O27
Molecular Weight	1237.4 g/mol
Synonyms	Polygalasaponin II; Polygalasaponin 2; Polygalasaponin B; 3-O-β-D-Glucopyranosyl-(1→3)-β-D-glucopyranosyl presenegenin 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-[β-D-apiofuranosyl-(1→3)]-4-O-acetyl-β-D-fucopyranosyl ester
EINECS	Contact for details

Quality Control

Every batch of Polygalasaponin Ii is manufactured and tested under strict quality management systems. Our products undergo rigorous identity, purity, and potency testing to ensure compliance with industry standards for high-purity reference materials. Certificates of Analysis (COA) detailing chromatographic purity, water content, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.