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5-Chlorothiophene-2-Boronic Acid CAS NO 162607-18-3
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CAS No.:162607-18-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
5-Chlorothiophene-2-Boronic Acid is a versatile and high-value organoboron building block, essential for modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecules through pivotal cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.
Application
- Pharmaceutical Intermediate: A key synthon for constructing novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
- Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides with improved efficacy.
- Material Science: Serves as a precursor for creating functionalized polymers, organic semiconductors, and liquid crystals.
- Chemical Research & Development: An indispensable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
- Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form biaryl and heterobiaryl structures.
- Ligand and Catalyst Development: Used to synthesize novel ligands and organometallic complexes for catalytic applications.
Basic Information
| Product Name | 5-Chlorothiophene-2-Boronic Acid |
| CAS No. | 162607-18-3 |
| Molecular Formula | C4H4BClO2S |
| Molecular Weight | 162.40 g/mol |
| Synonyms | (5-Chloro-2-thienyl)boronic acid; 5-Chloro-2-thiopheneboronic acid; 5-Chlorothiophene-2-boronic acid; 2-Borono-5-chlorothiophene; 5-Chloro-2-thienylboronic acid; 5-Chlorothiophen-2-ylboronic acid; 5-Chloro-2-thiophenylboronic acid |
| EINECS | Contact for details |
Quality Control
Our 5-Chlorothiophene-2-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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