Description

Erythro-n-Boc-o-Benzyl-L-Tyrosine Epoxide is a high-purity, protected amino acid derivative and a key chiral building block in advanced organic synthesis. This compound is critically important for the controlled introduction of the tyrosine moiety into complex molecular architectures, enabling precise stereochemical outcomes. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel peptide drugs and enzyme inhibitors.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate modified tyrosine residues with defined stereochemistry.
• Chemical Biology Research: Serves as a building block for creating activity-based probes and molecular tools to study biological pathways.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by providing a versatile, protected epoxide handle for further functionalization.
• Asymmetric Synthesis: Employed in the construction of complex natural products and non-natural amino acid derivatives requiring high enantiomeric purity.

Basic Information

Product Name	Erythro-n-Boc-o-Benzyl-L-Tyrosine Epoxide
CAS No.	162536-84-7
Molecular Formula	C22H25NO6
Molecular Weight	399.44 g/mol
Synonyms	(2S,3S)-3-[(tert-Butoxycarbonyl)amino]-4-phenyl-2-(phenylmethoxy)butyloxirane; Erythro-N-Boc-O-benzyl-L-tyrosine epoxide; (2S,3S)-1,2-Epoxy-3-[(tert-butoxycarbonyl)amino]-4-phenylbutyl benzyl ether; Boc-Tyr(Bzl)-epoxide (erythro); L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-, erythro-2,3-epoxybutyl ester; Amino acid epoxide derivative; Chiral tyrosine epoxide; Protected amino acid epoxide.
EINECS	Contact for details

Quality Control

Our Erythro-n-Boc-o-Benzyl-L-Tyrosine Epoxide is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (erythro isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.