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4-(2-Methyl-1,3-Dioxolan-2-Yl)Phenylboronic Acid CAS NO 162408-70-0
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CAS No.:162408-70-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-(2-Methyl-1,3-Dioxolan-2-Yl)Phenylboronic Acid is a versatile and valuable boronic acid derivative, serving as a key synthetic intermediate in modern organic chemistry. Its core value lies in its ability to participate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular assembly is critical for developing new active ingredients and functional molecules.
Application
- Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex aromatic and heteroaromatic systems.
- Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides through palladium-catalyzed coupling reactions.
- Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
- Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
- Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and affinity tags for studying protein interactions and enzyme activity.
- Custom Synthesis & Contract Manufacturing: A key reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.
Basic Information
| Product Name | 4-(2-Methyl-1,3-Dioxolan-2-Yl)Phenylboronic Acid |
| CAS No. | 162408-70-0 |
| Molecular Formula | C12H15BO4 |
| Molecular Weight | 234.06 g/mol |
| Synonyms | [4-(2-Methyl-1,3-dioxolan-2-yl)phenyl]boronic acid; 2-[4-(Boronophenyl)]-2-methyl-1,3-dioxolane; 4-(2-Methyl-1,3-dioxolan-2-yl)benzeneboronic acid; 2-Methyl-2-[4-(dihydroxyboranyl)phenyl]-1,3-dioxolane; (4-(2-Methyl-1,3-dioxolan-2-yl)phenyl)boronic acid; 4-(2-Methyl-[1,3]dioxolan-2-yl)-benzeneboronic acid; B-[4-(2-Methyl-1,3-dioxolan-2-yl)phenyl]boronic acid |
| EINECS | Contact for details |
Quality Control
Our 4-(2-Methyl-1,3-Dioxolan-2-Yl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your R&D and production needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 1.0% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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