Description

4-Cyclopropylmethoxy-3-Difluoromethoxybenzaldehyde is a high-purity aromatic aldehyde building block featuring both cyclopropylmethoxy and difluoromethoxy substituents. This compound is valued for its unique molecular architecture, which is critical for imparting specific physicochemical and biological properties in advanced synthetic pathways. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals and organic semiconductors, due to its tailored electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Cyclopropylmethoxy-3-Difluoromethoxybenzaldehyde
CAS No.	162401-78-7
Molecular Formula	C12H12F2O3
Molecular Weight	242.22 g/mol
Synonyms	3-(Difluoromethoxy)-4-(cyclopropylmethoxy)benzaldehyde; Benzaldehyde, 3-(difluoromethoxy)-4-(cyclopropylmethoxy)-; 4-(Cyclopropylmethoxy)-3-(difluoromethoxy)benzaldehyde; 3-Difluoromethoxy-4-cyclopropylmethoxybenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Cyclopropylmethoxy-3-Difluoromethoxybenzaldehyde is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.