Description

Propionylshikonin is a bioactive naphthoquinone derivative, a key constituent isolated from the roots of *Lithospermum erythrorhizon* (Zicao). This compound is valued for its potent pharmacological properties, serving as a critical intermediate and reference standard in advanced research and development. It is primarily sought after by pharmaceutical, biotechnology, and nutraceutical industries for its role in the study of anti-inflammatory, antimicrobial, and antitumor activities.

Application

• Pharmaceutical Research & Development: As a high-purity reference standard for pharmacokinetic, metabolic, and bioactivity studies.
• Natural Product Chemistry: A key analytical marker for the quality control and standardization of herbal extracts, particularly those derived from *Lithospermum* species.
• Biochemical Research: Investigation of cellular signaling pathways, enzyme inhibition, and mechanisms related to its anti-inflammatory and anticancer effects.
• Cosmeceutical Development: Exploration in formulations for its potential skin-soothing and anti-inflammatory benefits.
• Academic Research: Used in universities and research institutes for studies in medicinal chemistry and pharmacology.

Basic Information

Product Name	Propionylshikonin
CAS No.	162283-70-7
Molecular Formula	C21H22O6
Molecular Weight	370.40 g/mol
Synonyms	Propionylshikonin; Shikonin propionate; β,β-Dimethylacrylshikonin propionate; 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-en-1-yl]-1,4-naphthoquinone; 1,4-Naphthoquinone, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-pentenyl]-; (R)-5,8-Dihydroxy-2-((1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione
EINECS	Contact for details

Quality Control

Our Propionylshikonin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR, MS), to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere.

Specification

Item	Specification
Appearance	Reddish-brown to purple powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.