Description

4-Iodonaphthalene-1-Sulfonic Acid is a high-purity, functionalized naphthalene derivative that serves as a versatile building block in advanced organic synthesis. Its core value lies in the strategic combination of a reactive iodine substituent and a strongly acidic sulfonic acid group, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and specialty chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting specific receptors or requiring halogenated aromatic structures.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions to introduce the naphthalene sulfonate moiety into larger molecular frameworks.
• Dye and Pigment Manufacturing: Serves as an intermediate for creating specialized dyes, pigments, and optical brighteners with enhanced properties.
• Ligand and Catalyst Development: Employed in the research and development of novel ligands for catalysis and metal-organic complexes.
• Material Science Research: Used in the creation of functional polymers, conductive materials, and organic electronic components.
• Analytical Chemistry: Can be utilized as a derivatization agent or a standard for analytical method development.

Basic Information

Product Name	4-Iodonaphthalene-1-Sulfonic Acid
CAS No.	162109-21-9
Molecular Formula	C10H7IO3S
Molecular Weight	334.13 g/mol
Synonyms	1-Naphthalenesulfonic acid, 4-iodo-; 4-Iodo-1-naphthalenesulfonic acid; 4-Iodonaphthalenesulfonic acid; 4-Iodo-1-naphthalenesulphonic acid; 4-Iodonaphthalene-1-sulphonic acid; 4-Iodo-1-sulfonaphthalene; 4-Iodo-1-naphthalenesulfonate; 4-Iodonaphthalene-1-sulfonate
EINECS	Contact for details

Quality Control

Our 4-Iodonaphthalene-1-Sulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.