Description

Bicyclo[3.2.0]Heptan-2-One, 6,6-Difluoro- (9Ci) is a specialized fluorinated bicyclic ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique structural framework, which incorporates a strained bicyclic system and strategically placed fluorine atoms, enabling the development of novel molecules with tailored properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Research: Used in the synthesis of advanced herbicide and pesticide candidates, where the fluorinated bicyclic structure can enhance biological activity and environmental stability.
• Advanced Material Science: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials that benefit from its rigid, fluorinated core.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex, stereodefined molecular architectures via reactions like ring-opening, functionalization, or as a chiral pool component.
• Fluorine Chemistry Studies: A valuable substrate for investigating the influence of gem-difluoro substitution on the reactivity and physical properties of strained ketone systems.

Basic Information

Product Name	Bicyclo[3.2.0]Heptan-2-One, 6,6-Difluoro- (9Ci)
CAS No.	161941-21-5
Molecular Formula	C7H8F2O
Molecular Weight	146.14 g/mol
Synonyms	6,6-Difluorobicyclo[3.2.0]heptan-2-one; 6,6-Difluoro-2-bicyclo[3.2.0]heptanone; 6,6-Difluoro-2-oxobicyclo[3.2.0]heptane; 2-Bicyclo[3.2.0]heptanone, 6,6-difluoro-; 6,6-Difluoro-2-norbornanone (related structural name); Difluorinated Bicyclic Ketone; 161941-21-5
EINECS	Contact for details

Quality Control

Our Bicyclo[3.2.0]Heptan-2-One, 6,6-Difluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity by GC/HPLC, identity confirmation (IR, NMR), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Standard Grade)
Purity (GC/HPLC)	≥ 98.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.