Description

Cyclopropanecarboxylic Acid, 2-Fluoro-, Butyl Ester, (1R-Cis)- (9Ci) is a high-purity, chiral fluorinated cyclopropane derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and key intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to incorporate the unique steric and electronic properties of the fluorinated cyclopropane moiety into target molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, antivirals, and anti-inflammatory agents.
• Agrochemical Synthesis: Used as a building block for creating novel pesticides and herbicides, where the fluorocyclopropane structure can enhance biological activity and environmental stability.
• Asymmetric Synthesis: Employed in stereoselective reactions to construct complex molecules with high enantiomeric purity for applications in fine chemicals and catalysis.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric transformations.
• Material Science Research: Investigated as a monomer or modifier for creating specialty polymers with unique properties derived from the strained cyclopropane ring.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for studying biological mechanisms and enzyme interactions.

Basic Information

Item	Details
Product Name	Cyclopropanecarboxylic Acid, 2-Fluoro-, Butyl Ester, (1R-Cis)- (9Ci)
CAS No.	161814-30-8
Molecular Formula	C8H13FO2
Molecular Weight	160.18 g/mol
Synonyms	(1R,2S)-2-Fluorocyclopropanecarboxylic Acid Butyl Ester; (1R-cis)-2-Fluorocyclopropanecarboxylic Acid Butyl Ester; Butyl (1R,2S)-2-Fluorocyclopropanecarboxylate; Butyl (1R-cis)-2-Fluorocyclopropanecarboxylate; (1R,2S)-2-Fluorocyclopropanecarboxylic Acid n-Butyl Ester; Fluorocyclopropanecarboxylate Butyl Ester; Chiral Fluorocyclopropane Ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Fluoro-, Butyl Ester, (1R-Cis)- (9Ci) is produced under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption or contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.