Description

2,4-Pentanedione, 1,3,3-Trifluoro- is a specialized fluorinated diketone derivative, identified by CAS No. 161531-59-5. This compound is valued for its unique trifluoromethyl groups, which impart distinct chemical reactivity and physical properties, making it a versatile building block in advanced synthesis. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the preparation of fluorinated heterocycles and active pharmaceutical ingredients (APIs), leveraging the fluorine atoms to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of novel fluorinated pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Acts as a precursor for β-diketone ligands in coordination chemistry, useful for creating metal complexes with applications in catalysis and material science.
• Advanced Material Research: Employed in the synthesis of fluorinated polymers or specialty chemicals designed for unique surface properties, such as oil and water repellency.
• Organic Synthesis Building Block: Utilized in various condensation, cyclization, and fluorination reactions to introduce the 1,3-diketone motif with fluorine substitution.

Basic Information

Product Name	2,4-Pentanedione, 1,3,3-Trifluoro-
CAS No.	161531-59-5
Molecular Formula	C5H5F3O2
Molecular Weight	154.09 g/mol
Synonyms	1,1,1-Trifluoro-2,4-pentanedione; 1,1,1-Trifluoroacetylacetone; 1,1,1-Trifluoro-2,4-dioxopentane; 4,4,4-Trifluoro-2,4-pentanedione; TFAA; Trifluoroacetylacetone; 2,4-Pentanedione, 1,1,1-trifluoro-
EINECS	Contact for details

Quality Control

Every batch of 1,3,3-Trifluoro-2,4-pentanedione is produced and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure the material meets your specific research or production requirements. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.